PRF—platelet-rich fibrin— injections use your own blood to help rejuvenate your skin, especially in the under-eye area. PRF bears some similarities to the popular PRP treatments used in skin rejuvenation procedures. Double board-certified facial plastic surgeon Dr. Michael Somenek goes into more detail. “Platelet-rich fibrin (PRF) injections are essentially a form of under-eye fillers,” he says. “They’re considered the next generation of platelet-rich plasma (PRP) treatments, which are usually used to aid sports injuries. PRF is an autologous blood concentrate that uses your blood to help rejuvenate your skin.” Board-certified dermatologist Dr. Morgan Rabach adds that “platelet rich fibrin has been widely used for speeding up soft tissue and hard tissue healing.” “PRF consists of fibrin, platelets, leucocytes, cytokines and circulating stem cells,” she says of the treatment. “In a PRF procedure, blood is drawn from the patient and centrifuged at slower speeds than in a PRP (platelet-rich plasma) procedure,” board-certified dermatologist at MDCS Dermatology Dr. Brendan Camp adds. “The absence of an anticoagulant in the tube allows the formation of a spongy, gel-like product rich in platelets, stem cells, growth factors, and fibrin that can be injected into the skin to address signs of aging, hair loss, or skin healing.”